nuchal translucency scan london. This has occurred largely because the single most discriminatory marker, sonographic nuchal translucency thickness (NT), is only reliable at 11–13 weeks' gestation. nuchal translucency scan london

 
This has occurred largely because the single most discriminatory marker, sonographic nuchal translucency thickness (NT), is only reliable at 11–13 weeks' gestationnuchal translucency scan london 1

0 mm at 13 weeks. 00. You can have the test between 14 and 20 weeks of pregnancy. It uses ultrasound to measure the thickness of the fluid buildup at the back of the developing baby's neck. We provide whole range of pregnancy scans in south London (baby scans in south London). Protocol for measurement. The excess skin in the fetal neck region which is characteristic of Down syndrome individuals can be observed by ultrasound as either increased nuchal translucency (NT) in the first trimester 1 or increased nuchal skin-fold (NF) in the second trimester 2. Health care professionals who have obtained the certificate of competence in measurement of nuchal translucency. On this basis, pregnancy presenting. Nuchal translucency Scan, South London. Testing for Down syndrome During the ultrasound scan the sonographer measures the fluid beneath the skin at the back of your baby's neck - known as the nuchal translucency. Alderley Edge Medical Centre, Talbot Road, Alderley Edge,‘The value of the nuchal translucency scan in the era of cell-free DNA testing’ Diagnosis of fetal aneuploidies relies on invasive testing by chorionic villous sampling or amniocentesis in pregnancies that are identified by screening to be at high risk for such aneuploidies. 5 millimetres, therefore between 11 and 14 weeks of gestation. The optimal gestational age for measurement of fetal NT is 11 +0 to 13 +6 weeks. An NT scan, or nuchal translucency scan, is a non-invasive ultrasound screening for Down syndrome and other genetic conditions during pregnancy. An NT scan, or nuchal translucency scan, is a non-invasive ultrasound screening for Down syndrome and other genetic conditions during pregnancy. 8–9 weeks dating scan – some women choose to have an early ultrasound around 8-9 weeks. At Kings in London which is a world leader in scanning, they do not offer a blood test as it is considered to be less accurate than the NT (nuchal translucency) test. 1-6 The optimal gestational age to perform NT. 4. Accept Cookie Policy. A higher NT measurement may indicate a risk of Down's syndrome and other chromosomal conditions. Nuchal Translucency Scan Includes NT measurement, nasal bone and hormone biochemistry blood test (free ß-hCG and PAPP-A) Read More. ) Out of 640 cases, 341 women who underwent mid-trimester scan in our. Date the pregnancy. For babies with a size of 45-84mm, the normal nuchal translucency will be less than 3. My nuchal translucency scan report says the fetal right femur length is 4. During a test for nuchal translucency (NT), an ultrasound is performed to measure the collection of fluid between the fetus’s spine and the skin in the area of the nape of the neck. Nuchal translucency scan. This cost wouldn't much matter if I was having this test at the start of next year. Blood test for human chorionic gonadotropin (hCG) – Measures hormone levels associated with Down syndrome risk. AE Abstract. Prenat Diagn 31 7 15; 13. BMJ 1992;304(6831):867-9. The RANZCR provides a credentialling program for providers of nuchal translucency scans. A Guide to Understanding Prenatal Screening. The nuchal translucency measurement is a test to assess the risk of chromosomal abnormality, in particular of trisomy 21. H. Done in first trimester. 2017;37:235–243. A risk-score is calculated based on the values from the double-test and the nuchal translucency and the maternal age. During the last decade a strong association between increased nuchal translucency (NT) at ultrasound examination at 11–14 gestational weeks and DS has been established 3, 4. Nuchal translucency (NT). Nuchal translucency (NT) measurement is the most powerful screening tool for Down syndrome and congenital malformations, especially cardiac anomaly [ 1 - 11 ]. Baby 3d 4d scan: nt scanScan nt results blood work normal Ultrasound nt scan: price, purpose, results & timing [2023]Nt ultrasound scan nuchal translucency baby fetal normal increased screening down trimester thickness which syndrome nasal bone question pregnancy fetus. Amniocentesis is another test that checks for birth defects. 2-3 December 2023, London, UK For more information. Nuchal translucency. Clinic Hours. The gestational age must be between 11 weeks and 13 weeks and six days. We advise you to book at least 2-3 weeks […]Nuchal translucency must be done between 11 weeks 0 days and 13 weeks 6 days menstrual gestational age. 7 mm at 10 weeks’ gestation to 1. It includes multiple components and is highly dependent on the operator. org Consultation with our Obstetrician £250. 139 fetuses with NT ≥ 2. At King's College Hospital and the Fetal Medicine Centre, London, chorionic villous sampling for fetal karyotyping is done at the parents' request after screening for Down's syndrome by ultrasound examination with or without maternal serum biochemistry at 11-13 +6 weeks, at which the fetal crown-rump length and NT are. A total of 139 women with gestational 11-14 weeks whose fetuses were detected with increased NT (NT ≥ 2. During a nuchal translucency screening, an ultrasound scan is used to take a measurement of the thickness of the back of the neck of your baby. The 11-13+6 weeks scan. The nuchal translucency test correctly finds Down syndrome in 64 to 70 out of 100 fetuses who have it. 928 for methods A, B, and C, respectively. Nuchal translucency is the name for the fluid behind the neck of your baby. King's College Hospital and Department of Fetal Medicine, University College, London, UK. Some people opt to have prenatal screening tests, while others do not. A prospective study was conducted on 400 pregnant patients to determine the fetal sex by ultrasound scan between 11–13+6 weeks of gestation. 1, 2 Investigation of fetuses with increased NT typically comprises rapid aneuploidy. Mean arterial pressure; Uterine artery PI; Nuchal translucency; Ductus venosus PIV;. why and when. Book Consultant - £550. Inclusion of PlGF into the first trimester combined test (maternal age, PAPP-A, free beta-hCG) and nuchal translucency would increase the detection rate by 0. screening necessitates the availability of a diagnostic test and chorionic villus sampling before this. Fetal medicine centre in London. It is not an unusual condition to have clear or fluid space at the back of the baby’s. Nuchal translucency; Performance audits. footnote 1; It's possible that a screening test will show that the baby has an increased chance of having a problem when he or she doesn't have the problem. Methods This observational single-cohort study was. The Nuchal Translucency scan is offered from 11+3 to 13+6 weeks of pregnancy to screen for the most common chromosomal conditions including Down’s syndrome, Edwards’ Syndrome and Patau’s syndrome. Pre-eclampsia screen 4. This early increased NT, with NT ≥ 2. The Birth Company Ground Floor 32 Wimpole Street London W1G 8GT. 1002/pd. The early detection thus prevents various health conditions in the fetus. 2. This screening test does not diagnose a chromosomal abnormality, but may identify. 5 weeks and 13 weeks, six days. FMF. Screening protocols which use NT together with maternal serum markers at 10–13 weeks can achieve a much better screening performance than do second-trimester serum-only. In all cases, an attempt was. Your first scan with the NHS is likely to be the nuchal translucency/dating scan at 11-13 weeks. The scan is usually performed transabdominally. Done in first trimester. Fetal nuchal translucency: ultrasound screening for chromosomal defects in the first trimester of. Elsevier: London, pp 123-59. Nuchal translucency screening is a noninvasive test doctors perform during pregnancy. The TDL Veriseq v2 by Illumina test is available from as early as 10 weeks of pregnancy, for early screening before the NHS Nuchal Translucency scan. 1136/bmj. If this area is thicker than normal, it can be an early sign of Down syndrome, trisomy 18, or heart problems. Nuchal Translucency Scan Includes NT measurement, nasal bone and hormone biochemistry blood test (free ß-hCG and PAPP-A) Read More. It misses Down syndrome in 30 to 36 out of 100 fetuses. See full list on fetalmedicine. The FMF with the support of an international group of experts, has introduced an educational programme both for healthcare professionals and doctors and in the last 25 years the. Cervical length items 55757 and 55758. free of charge rescans if we can't complete the primary purpose of the scan. My annual deductible is $3,000, but unfortunately resets January 1st. 5 mm, and those without associated anomalies. The doctor is concerned about the nuchal translucency measurement / amount of fluid in the fold of the neck. #4 Neutral fetal position. Bond Street Oxford Circus. During the last decade a strong association between increased nuchal translucency (NT) at ultrasound examination at 11–14 gestational weeks and DS has been established 3, 4. The authors concluded that PlGF at 11 weeks to 13 weeks 6 days has the potential to be included as a marker for the detection of pregnancies with trisomy 21. Nuchal translucency (NT) measurement has been shown to be increased in fetuses with common chromosomal abnormalities (trisomies 21, 18 and 13 and monosomy X) and structural abnormalities, particularly cardiac defects, and single-gene disorders. 5%. London: Fetal Medicine Foundation; 2004. After exclusion of three cases with obvious first-trimester anomalies and two with incomplete outcome data, 42 remained for analysis. 5 mm with a 45–84 mm crown-rump length (CRL), as detected by karyotyping or CMA. Prenat Diagn. Appointment duration 30 - 40 minutes. 5‐3. The nuchal translucency (NT) thickness measurements scan was developed in the 1990s, and at the time was the best screening option for Down’s syndrome offering about 62% accuracy and a 5% false positive rate. 2017;37:235–243. Because NT measurement at 12–14 weeks is now routinely offered at many centers, it is of interest to. Definitely too early for your NT test. The nuchal translucency (NT) measurement in combination with serum biomarkers and maternal age, resulted in the first trimester combined screening (FTCS) program. Citation 6, Citation 8 The procedure of the NT measurement is the same as that for the measurement of the fetal CRL with an optimal. Many pregnant women decide to have this test. 0 to 3. (12. Your sonographer will choose a method based on several considerations, including how far along your pregnancy is and your body shape. The other part is a specific blood test from the mother. About Us. Secondary objectives were to analyze these results according to NT thickness, below or above 3. An NT scan is a common screening test that occurs during the first trimester of pregnancy. to measure the fetal heart rate. With over 25 years of experience and. Nuchal Translucency Scan. The NT scan must be done when you're between 11. The 11–13-week scan was carried out by one of 476 sonographers. All these risks increase in proportion to the increase in nuchal translucency thickness [1,4]. A nuchal translucency scan is offered to all pregnant women in the first trimester along with a blood test. The latter relies on accurate measurement of the fetal nuchal translucency (NT) thickness and assessment of the nasal bone, which necessitates examination of the mid-sagittal view of the fetal face 4, 5. During a test for nuchal translucency (NT), an ultrasound is performed to measure the collection of fluid between the fetus’s spine and the skin in the area of the. A nuchal translucency measurement greater than 2. Typically, a routine scan to check on. So the ultrasounds alone are going to be $681. The 11-13 weeks scan; Preeclampsia screening;. Methods. Mon: 08:00 - 20:00: Tue:Most of the times, nuchal translucency is caused by Down Syndrome, but in this case I can rule that out, since the fetus has a nasal bone. Search. footnote 1; It's possible that a screening test will show that the baby has an increased chance of having a problem when he or she doesn't have the problem. The nuchal (say "NEW-kuhl") translucency screening is a test done during pregnancy. In particular, for Down syndrome, there is a 1/30 chance of the fetus having the disease. Routine measurement of NT thickness combined with first-trimester maternal. INTRODUCTION. The procedure is performed by a specially trained ultrasound technician, and the results are read by a radiologist who also has specific training. What is the Nuchal Translucency Scan (NT)? This is a simple non-invasive test best performed between 12-14 weeks of pregnancy to assess the risk of having a baby with a chromosome abnormality. 7%) in 2007 and lowest (0. 8%) postnatally. 0 fewer births of babies with Down's syndrome than the nuchal translucency measurement at a total cost of £276 000. NT of infants was measured at a CRL of 45–84 mm, and gestational age was determined using CRL during the 11–14-week scan. The combination of nuchal translucency thickness, PAPP-A, and hCG detects 87% of cases of trisomy 21 at 11 weeks, 85% at 12 weeks, and 82% at 13 weeks, with a 5% false-positive rate 8. This is also called the nuchal translucency and is located at the back of the neck of the baby. 12 – 13+6 week nuchal translucency scan 19+ week anatomy scan. Try not to stress, if you’re really worried you should speak with your doctor. During a nuchal translucency screening, an ultrasound scan is used to take a measurement of the thickness of the back of the neck of your baby. 8–9 weeks dating scan – some women choose to have an early ultrasound around 8-9 weeks. It measures the fluid under the skin at the back of the baby’s neck. Submission of a logbook of 3 images showing correct assessment of the nasal bone. Batch MoMs calculation; Batch preeclampsia risks; Research . Nuchal translucency is the name for the fluid behind the neck of your baby. Fetal nuchal translucency scan and early prenatal diagnosis of chromosomal abnormalities by rapid aneuploidy screening: observational study BMJ. 4 mm (21 of 534, 3. Purpose To evaluate the performance of chromosomal microarray analysis (CMA) in fetuses with nuchal translucency (NT) > 95th percentile. nd. It increases with crown-rump length and the median NT increases from 1. The median and 95th centile at 11 +0 week was 1. The nuchal (say "NEW-kuhl") translucency screening is a test done during pregnancy. Nuchal translucency scan. Test. Date the pregnancy. Nuchal Translucency) is a exam which consists of a external ultrasound, harmless for the unborn child, with which the thickness of a collection of liquid located under the fetal neck is measured, that is, in practice, the distance between the skin of the nape and the occipital bone of the skull. Attendance of the internet based course on the 11-13 weeks scan. As mentioned by others, these tests are notoriously inaccurate accurate and can give false positives. Nuchal translucency (NT) is the sonographic appearance of a subcutaneous collection of fluid behind the fetal neck. London | SW1P 1WG. Elsevier: London, pp 123-59. c. The added value of detailed early anomaly scan in fetuses with increased nuchal translucency. 0) per affected baby prevented. 5 mm (147 of 491, 29. The most common problem is that the. The estimated last date a. Nuchal translucency scan. 9%) at the 18–24-week scan, in 10 (4. With respect to frequencies of repeat per year, it was highest (26. An increased nuchal translucency (NT) >3. Nuchal translucency scan. First-trimester screening for Down's syndrome that includes the use of ultrasonography to assess nuchal translucency has become widespread since its introduction by Nicolaides and colleagues in. 20. Nuchal translucency scan. The nuchal translucency is the fluid-filled space at the back of your baby’s neck (the nuchal fold). If your healthcare provider suspects something. In cases with early increased NT 2. The NHS now offers the ‘combined test’ at 11-14 weeks which includes a nuchal translucency scan along with a blood test (for PAPP-A and HCG proteins) with. Purpose To evaluate the performance of chromosomal microarray analysis (CMA) in fetuses with nuchal translucency (NT) > 95th percentile. A Nuchal Translucency (NT) scan is a screening test to assess if a baby is likely to have Down’s syndrome or other chromosomal abnormalities. Source: Images courtesy of A/Prof Simon Meagher, University of Melbourne TABLE 1 Conditions associated with increased NT after low‐risk. This test measures the size of the clear tissue, called the nuchal translucency, at the back of your baby. 2mm and 1. Submission of a logbook of 3 images showing correct assessment of the nasal bone. NT scan is a popular screening test done during the first trimester. 5 mm) in our hospital from July 2016 to December 2018 were selected. In 113 (53. When fetal nuchal translucency was combined with maternal serum free-beta-human chorionic gonadotropin and pregnancy-associated plasma protein-A in prospective studies in a total of 44,613 pregnancies, including 215 fetuses with trisomy 21, the detection rate was 87. Nuchal translucency screening involves having an ultrasound of your abdomen in the. Identify multiple pregnancies. I’d like to hear your honest stories. Further workup If abnormal NT and screening test results show an increased risk of less than 1 in 300, further workup may be carried out based on. 2017;37:235–243. This is an area of tissue at the back of an unborn baby's neck. This is an area of tissue at the back of an unborn baby’s neck. The new doctor I saw was more optimistic and didn’t seem too concerned that it had. fetalmedicine. Of these, 640 women underwent scan between 11 and 13 +6 weeks for combined first trimester screening (screening for aneuploidy using NT and double markers. 5mm. doi:10. Copy number variation sequencing (CNV‐seq) technique was used to analyze the genetic etiology of fetuses with increased nuchal translucency (NT). Mean arterial pressure; Uterine artery PI; Nuchal translucency; Ductus venosus PIV; Serum sFLT-1; Serum PLGF; Serum PAPP-A; Serum free β-hCG; Research tools . Both came back very low which was such a relief. Also, in the early 1990s, several papers -most prominently coming from the Fetal Medicine Foundation in London -demonstrated that an enlarged nuchal translucency (NT) measurement combined with. The Birth Company Ground Floor 32 Wimpole Street London W1G 8GT. London. In addition, various sonographic markers such as nuchal fold thickness and femur length in second trimester were introduced, and the nuchal translucency (NT) became important as the early screening method for chromosomal abnormality (1-3). This measurement is used with your blood. Excess amounts of fluid, however, indicate the possibility of chromosomal disorders. Nuchal Translucency Scan – 12 weeks. If it's abnormally large, containing more fluid than usual, it may indicate Down syndrome (trisomy 21) or another genetic condition called trisomy 18. FIGURE 1 (A) A normal nuchal translucency (NT) measurement in a fetus at 13 weeks 0 days gestation. footnote 1; It's possible that a screening test will show that the baby has an increased chance of having a problem when he or she doesn't have the problem. Normal babies accumulate fluid under the skin behind the head and neck between 9 and 14 weeks of pregnancy, however, excess fluid has been associated with chromosome abnormalities such as Down syndrome. Nuchal translucency (NT) measurement is widely used as a marker of fetal abnormalities both of chromosomal and non-chromosomal origin [1–3]. uk Contact a Family is a charity which provides support, advice and. The Fetal Medicine Foundation (FMF) established the strict guideline for NT measurement. 01) between two-dimensional (2D) and a deviation of 31-40° and -0. Meiri Robertson MB, ChB BSc, MEdScHon, Fetal Medicine Diploma (FMF, London) Fetal Medicine Unit, Women and Children's Health Services, The Canberra Hospital, Canberra, Australian Capital Territory, Australia. . Traditionally three factors are used to calculate the risk of trisomies: crown. The nuchal translucency measurement can be obtained using transabdominal US in about 95% of patients [5,17,22,23]. 5 mm warrants referral to a Fetal Medicine Unit for an extensive work‐up. This is the measurement behind the neck of your baby. We’re waiting anxiously for the NIPT testing results. Nearest Underground Tube Stations. Therefore, in many countries a routine offer of an ultrasound scan at 11–14 weeks has been introduced in addition to a routine offer of a mid-trimester scan. Our policy is to scan the fetus at the time of detection of a nuchal translucency above 3. 8 Specimens with increased NT were divided into five groups based on the NT thickness: NT ≥2. Nuchal translucency. fetalmedicine. August 15, 2023 | by Ash612xo. A nuchal translucency scan is offered to all pregnant women in the first trimester along with a blood test. 0 to 3. Introduction. During this time, the baby's length from crown to rump is between 45 mm and 84 mm. At 12 Weeks: Nuchal Translucency Scan. The integrated test results in 2. 0 mm (71 of 80,219, 0. London W1G 8GT. com 020 3687 2939. Down’s, Edwards’ and Patau’s syndromes screening. 9%) patients had normal NT and DV-RAV. Babies who are developing normally have fluid under the skin. It helps determine your baby’s risk of congenital conditions like Down syndrome. g. Clinical History a. Elsevier: London, pp 123-59. The next pregnancy scan is the 12 week Nuchal Translucency Scan which assesses the likelihood of Down's syndrome and other chromosomal conditions. FMF fellowships; Diploma in fetal medicine; Education . The measurement of fetal NT thickness at the 11–14-week scan has been co. why and when. Traditionally three factors are used to calculate the risk of trisomies: crown. Copy number variation sequencing (CNV-seq) technique was used to analyze the genetic etiology of fetuses with increased nuchal translucency (NT). 5 weeks €125. Although a normal nuchal translucency is reassuring, nuchal translucencyHigh Nuchal Translucency result at 12 week scan! 37 answers / Last post: 06/10/2016 at 7:26 pm. Nuchal translucency. It's called the combined test because it combines an ultrasound scan with a blood test. The NT is still thickened, 4. Nuchal translucency (NT). 8in. a) Hyper flexed head position will ______ the NT measurement. 8in. Major heart defects. It can be done earlier in pregnancy than amniocentesis. Before you arrive for your appointment we strongly encourage you to decide which screening test you would like to use to assess the results of your ultrasound. 1002/pd. The 11-13 weeks scan; Preeclampsia screening; Fetal abnormalities; Fetal echocardiography; Doppler ultrasound; Cervical assessment; Placenta Accreta Spectrum (PAS) Case reports;. Ultrasound Direct is the trusted choice to provide the best possible ultrasound scan experience. . The test is done between 10 and 13 weeks of. Abstract Objective Identify placental pathology-related complications, labor and neonatal outcomes in pregnancies complicated by pathological nuchal translucency (NT) with normal microarray analysi. Opens a new window [Accessed July 2017] GEC-KO. This can offer you peace of mind about the development of your baby and allow you to make an informed decision in moving forward. org. In fetuses with Down syndrome and other chromosomal abnormalities, fluid tends to accumulate in this location, making the space. Ultrasound – Measures nuchal translucency thickness at the back of the fetus’s neck. Since chromosomal abnormalities can result in impaired cardiovascular development, a nuchal. Over the past decade, nuchal translucency thickness (NT. or when your baby measures between 45mm (1. Note the possible presence of funnelling at the internal os. Nuchal translucency; Performance audits. For instructions on how the excel file should be formatted, please click here . Measure the distance between the internal and external os. Both screening and diagnostic testing are offered to. Nicolaides KH, Azar G, Byrne D, et al. The median maternal age was 33 years (range 14–47 years), with 456 (35. If you choose to have the test, you will have a blood sample taken. The guideline is used worldwide and requires a certification and annual re-audit for NT. The scan measures the clear, translucent space in the tissue at the back of your baby's neck (nuchal translucency). The 11-13+6 weeks scan, 1 112 London, UK; 12. 00 During the last decade a strong association between increased nuchal translucency (NT) at ultrasound examination at 11–14 gestational weeks and DS has been established 3, 4. The latter relies on accurate measurement of the fetal nuchal translucency (NT) thickness and assessment of the nasal bone, which necessitates examination of the mid-sagittal view of the fetal face 4, 5. Submission of 3 images demonstrating color flow mapping and waveforms of the uterine artery at 11-13 weeks. This scan reviews the fetal viability, number, structure and/or to assess the likelihood of aneuploidy. Items 55757 (R) and 55758 (NR) are to assess the cervical length of the patient to determine risk of preterm labour and can be claimed for any pregnancy. Nuchal Translucency Scan Includes NT measurement, nasal bone and hormone biochemistry blood test (free ß-hCG and PAPP-A) Read More. The blood test, which you may have any time after 10 weeks or on the same day as your. She did not specify an exact measurement, but I can tell on the. The nuchal translucency scan is a routine prenatal assessment helps your doctor determine the risk of your baby developing a chromosomal difference. 020 7725 0528 [email protected] Wimpole Street, London Opening Times. The nuchal translucency scan looks at and measures the fluid behind baby’s neck and under their skin via ultrasound, explains Rachel Blair Danis, MD, a reproductive endocrinologist and ob-gyn with RMA of New York. Nuchal translucency (NT), defined as the subcutaneous accumulation of fluid behind the fetal neck, can effectively be measured by an ultrasound investigation between 11 and 13+6 weeks of gestation. Wimpole Street, London. 2. Nuchal Translucency Scan Includes NT measurement, nasal bone and hormone biochemistry blood test (free ß-hCG and PAPP-A) Read More. 4997. The present article aims at summarizing the ideal protocol for the measurement of the. Methods A total of 139 women with gestational 11‐14 weeks whose fetuses were detected with increased NT (NT ≥ 2. FMF certification in measurement of nuchal translucency. The “First Things First” series will deal with all aspects of the nuchal translucency (NT) scan, one at a time, in the current and forthcoming issues of the Journal. 655197. Nicolaides KH, Brizot ML, Snijders RJM. Nicolaides K. ” The doctor thought there could be some heart malformation that. 4% (n=27). Nuchal translucency; Ductus venosus PIV; Serum sFLT-1; Serum PLGF; Serum PAPP-A; Serum free β-hCG; Research tools . It measures the growing baby’s risk of having certain chromosomal abnormalities and heart conditions. fetalmedicine. 2-3 December 2023, London, UKA nuchal translucency scan (NT scan) is an ultrasound screening test for assessing whether your baby is likely to have Down's syndrome. and between 18 and 21 weeks. Mean arterial pressure; Uterine artery PI; Nuchal translucency; Ductus venosus PIV;. or when your baby measures between 45mm and 84mm, crown to rump. 01969 * Crown-rump length). 5mm. Advances in Fetal Medicine. International surveys have shown that patients with low risks of aneuploidy have a better pregnancy outcome than expected. NT increases with gestational age and therefore with CRL measurement 1 , by c.